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A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells.
Mellott, Drake M; Tseng, Chien-Te; Drelich, Aleksandra; Fajtová, Pavla; Chenna, Bala C; Kostomiris, Demetrios H; Hsu, Jason; Zhu, Jiyun; Taylor, Zane W; Tat, Vivian; Katzfuss, Ardala; Li, Linfeng; Giardini, Miriam A; Skinner, Danielle; Hirata, Ken; Beck, Sungjun; Carlin, Aaron F; Clark, Alex E; Beretta, Laura; Maneval, Daniel; Frueh, Felix; Hurst, Brett L; Wang, Hong; Kocurek, Klaudia I; Raushel, Frank M; O'Donoghue, Anthony J; de Siqueira-Neto, Jair Lage; Meek, Thomas D; McKerrow, James H.
Afiliación
  • Mellott DM; Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas 77843.
  • Tseng CT; Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas, 77755-1001.
  • Drelich A; Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas, 77755-1001.
  • Fajtová P; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
  • Chenna BC; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 16610 Prague, Czech Republic.
  • Kostomiris DH; Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas 77843.
  • Hsu J; Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas 77843.
  • Zhu J; Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas, 77755-1001.
  • Taylor ZW; Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas 77843.
  • Tat V; Department of Chemistry, Texas A&M University, 301 Old Main Drive, College Station, Texas 77843.
  • Katzfuss A; Current address: Biological Sciences Division, Pacific Northwest National Laboratory, 902 Battelle Blvd, Richland, WA 99353.
  • Li L; Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas, 77755-1001.
  • Giardini MA; Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas 77843.
  • Skinner D; Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas 77843.
  • Hirata K; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
  • Beck S; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
  • Carlin AF; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
  • Clark AE; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
  • Beretta L; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, CA 92037, USA.
  • Maneval D; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
  • Frueh F; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
  • Hurst BL; Selva Therapeutics, Department of Animal, Dairy, and Veterinary Sciences, 5600 Old Main Hill, Utah State University, Logan, Utah, 84322.
  • Wang H; Selva Therapeutics, Department of Animal, Dairy, and Veterinary Sciences, 5600 Old Main Hill, Utah State University, Logan, Utah, 84322.
  • Kocurek KI; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, 5600 Old Main Hill, Utah State University, Logan, Utah, 84322.
  • Raushel FM; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, 5600 Old Main Hill, Utah State University, Logan, Utah, 84322.
  • O'Donoghue AJ; Department of Chemistry, Texas A&M University, 301 Old Main Drive, College Station, Texas 77843.
  • de Siqueira-Neto JL; Department of Chemistry, Texas A&M University, 301 Old Main Drive, College Station, Texas 77843.
  • Meek TD; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
  • McKerrow JH; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
bioRxiv ; 2020 Oct 30.
Article en En | MEDLINE | ID: mdl-33140046
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2020 Tipo del documento: Article