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A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome Complex.
Angelbello, Alicia J; Benhamou, Raphael I; Rzuczek, Suzanne G; Choudhary, Shruti; Tang, Zhenzhi; Chen, Jonathan L; Roy, Madhuparna; Wang, Kye Won; Yildirim, Ilyas; Jun, Albert S; Thornton, Charles A; Disney, Matthew D.
Afiliación
  • Angelbello AJ; Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458, USA.
  • Benhamou RI; Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458, USA.
  • Rzuczek SG; Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458, USA.
  • Choudhary S; Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458, USA.
  • Tang Z; Department of Neurology, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA.
  • Chen JL; Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458, USA.
  • Roy M; Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
  • Wang KW; Department of Chemistry, Florida Atlantic University, Jupiter, FL 33458, USA.
  • Yildirim I; Department of Chemistry, Florida Atlantic University, Jupiter, FL 33458, USA.
  • Jun AS; Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
  • Thornton CA; Department of Neurology, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA.
  • Disney MD; Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458, USA. Electronic address: disney@scripps.edu.
Cell Chem Biol ; 28(1): 34-45.e6, 2021 01 21.
Article en En | MEDLINE | ID: mdl-33157036
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Distrofia Endotelial de Fuchs / Expansión de Repetición de Trinucleótido / Bibliotecas de Moléculas Pequeñas / Exosomas / Distrofia Miotónica Límite: Female / Humans / Male Idioma: En Revista: Cell Chem Biol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Distrofia Endotelial de Fuchs / Expansión de Repetición de Trinucleótido / Bibliotecas de Moléculas Pequeñas / Exosomas / Distrofia Miotónica Límite: Female / Humans / Male Idioma: En Revista: Cell Chem Biol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos