Villous atrophy persistence in celiac disease despite following a gluten-free diet must be clarified.
Rev Esp Enferm Dig
; 113(1): 76, 2021 01.
Article
en En
| MEDLINE
| ID: mdl-33200613
ABSTRACT
We read with great interest the article recently published in REED by Shadegi et al. Villous atrophy (VA) persists in 35 % and 23.7 % of celiac disease (CD) patients for six and 24 months, respectively, after following a gluten-free diet (GFD). The authors think that the time following a GFD must be longer than two years in some patients to achieve mucosal healing and we agree with this. Our experience comes from a short series of ten females and three males with CD, diagnosed at an average age of 36 years (15-72) based on serology (anti-TG2 > 10 IU/ml or anti-Em positive) and a duodenal biopsy showing VA. All cases followed a GFD, according to the anamnesis and underwent a second duodenal biopsy and anti-TG2 determination after 42 (10-202) months. Immunogenic peptides of gluten (IPG) in feces were determined in four patients.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedad Celíaca
/
Dieta Sin Gluten
Límite:
Adult
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Female
/
Humans
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Male
Idioma:
En
Revista:
Rev Esp Enferm Dig
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2021
Tipo del documento:
Article