Efficacy of Phase 1 of Life Goals Programme on symptom reduction and mood stability for bipolar disorder.
J Affect Disord
; 281: 949-957, 2021 02 15.
Article
en En
| MEDLINE
| ID: mdl-33229019
ABSTRACT
BACKGROUND:
Life Goals Programme (LGP) was developed as a psychological intervention for bipolar disorder, with its structured 6-session psychoeducation phase (Phase 1) targeting understanding of the disorder, medication adherence, early warning signs, and coping with symptoms and triggers. The present study tested the efficacy of Phase 1 of the LGP on symptom recovery and moment-by-moment mood stability, as well as medication adherence and quality of life.METHODS:
Adults with bipolar disorder were randomly allocated to the LGP condition (six weekly group sessions) or the waitlist condition (six weeks of standard care, followed by the same LGP intervention). Participants were assessed before and after treatment, and at 6-month follow up. Waitlist participants were additionally assessed at baseline. Assessment included a clinical interview (SCID, MADRS, YMRS, and HAM-A), self-reported questionnaires, and 6-day experience sampling assessment on a mobile device.RESULTS:
64 out-patients with bipolar disorder (44 Bipolar I and 20 Bipolar II subtypes) participated in this study. LGP was well received and attended. Following LGP, there were significant improvements in knowledge about illness and level of anxiety, which were of large effect sizes and sustained at 6-month follow-up. Experience sampling assessment revealed small but significant improvements in moment-by-moment mood stability. Improvement in medication adherence was significant at 6 months and was of a moderate-to-large effect size. Changes in anxiety and mood stability were significantly greater following LGP than standard care.LIMITATIONS:
Our results warrant further testing against active control.CONCLUSIONS:
There was a robust improvement in emotional regulation following the 6-week LGP.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trastorno Bipolar
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Qualitative_research
Límite:
Adult
/
Humans
Idioma:
En
Revista:
J Affect Disord
Año:
2021
Tipo del documento:
Article