Neonatal red blood cell transfusion.
Vox Sang
; 116(4): 366-378, 2021 Apr.
Article
en En
| MEDLINE
| ID: mdl-33245826
ABSTRACT
Transfusions are more common in premature infants with approximately 40% of low birth weight infants and up to 90% of extremely low birth weight infants requiring red blood cell transfusion. Although red blood cell transfusion can be life-saving in these preterm infants, it has been associated with higher rates of complications including necrotizing enterocolitis, bronchopulmonary dysplasia, retinopathy of prematurity and possibly abnormal neurodevelopment. The main objective of this review is to assess current red blood cell transfusion practices in the neonatal intensive care unit, to summarize available neonatal transfusion guidelines published in different countries and to emphasize the wide variation in transfusion thresholds that exists for red blood cell transfusion. This review also addresses certain issues specific to red blood cell processing for the neonatal population including storage time, irradiation, cytomegalovirus (CMV) prevention strategies and patient blood management. Future research avenues are proposed to better define optimal transfusion practice in neonatal intensive care units.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Unidades de Cuidado Intensivo Neonatal
/
Transfusión de Eritrocitos
Tipo de estudio:
Guideline
Límite:
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
Vox Sang
Año:
2021
Tipo del documento:
Article
País de afiliación:
Canadá