Cholesterol: Bioactivities, Structural Modification, Mechanisms of Action, and Structure-Activity Relationships.
Mini Rev Med Chem
; 21(14): 1830-1848, 2021.
Article
en En
| MEDLINE
| ID: mdl-33402086
ABSTRACT
Cholesterol, steroid alcohol, was discovered by M.E. Chevreul in 1815. Cholesterol and its derivatives showed a large variety of biological properties such as anticancer activity, anticardiac activity, anti-inflammatory activity, antimicrobial activity, anti-psychotic activity, antioxidant activity, drug-loaded activity, etc. In this mini-review, the advances of structural modification of cholesterol from 2014 to 2020 are summarized. In addition, the bioactivities, mechanisms of action and structureactivity relationships of cholesterol and its related derivatives are also discussed.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Colesterol
/
Antiinflamatorios
Límite:
Humans
Idioma:
En
Revista:
Mini Rev Med Chem
Asunto de la revista:
QUIMICA
Año:
2021
Tipo del documento:
Article
País de afiliación:
China