miR-219a suppresses human trophoblast cell invasion and proliferation by targeting vascular endothelial growth factor receptor 2 (VEGFR2).

Zhou, Guiju; Li, Zhifang; Hu, Pin; Wang, Jing; Fu, Juanjuan; Wei, Bing; Zhang, Yu

Zhou, Guiju; Li, Zhifang; Hu, Pin; Wang, Jing; Fu, Juanjuan; Wei, Bing; Zhang, Yu.

Afiliación

Zhou G; Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Anhui Medical University, 678 Furong Road, 230000, Hefei, People's Republic of China.
Li Z; Anqing Municipal Hospital, Anhui Medical University, Anqing, China.
Hu P; Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Anhui Medical University, 678 Furong Road, 230000, Hefei, People's Republic of China.
Wang J; Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Anhui Medical University, 678 Furong Road, 230000, Hefei, People's Republic of China.
Fu J; Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Anhui Medical University, 678 Furong Road, 230000, Hefei, People's Republic of China.
Wei B; Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Anhui Medical University, 678 Furong Road, 230000, Hefei, People's Republic of China. bingw1@sohu.com.
Zhang Y; Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Anhui Medical University, 678 Furong Road, 230000, Hefei, People's Republic of China. zhangy_11@21cn.com.

J Assist Reprod Genet ; 38(2): 461-470, 2021 Feb.

Article en En | MEDLINE | ID: mdl-33405003

Asunto(s)

Proliferación Celular/genética; MicroARNs/genética; Preeclampsia/genética; Receptor 2 de Factores de Crecimiento Endotelial Vascular/genética; Apoptosis/genética; Línea Celular; Movimiento Celular/genética; Femenino; Humanos; FN-kappa B/genética; Fosfatidilinositol 3-Quinasas/genética; Placenta/metabolismo; Placenta/patología; Preeclampsia/metabolismo; Preeclampsia/patología; Embarazo; Proteínas Proto-Oncogénicas c-akt/genética; Transducción de Señal/genética; Trofoblastos/metabolismo

Palabras clave

Invasion; PI3K/AKT/NF-κB signaling; Proliferation; Trophoblast; VEGFR2; miR-219a

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Preeclampsia / Receptor 2 de Factores de Crecimiento Endotelial Vascular / MicroARNs / Proliferación Celular Límite: Female / Humans / Pregnancy Idioma: En Revista: J Assist Reprod Genet Asunto de la revista: GENETICA / MEDICINA REPRODUTIVA Año: 2021 Tipo del documento: Article

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