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Natural cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling.
Hayn, Manuel; Blötz, Andrea; Rodríguez, Armando; Vidal, Solange; Preising, Nico; Ständker, Ludger; Wiese, Sebastian; Stürzel, Christina M; Harms, Mirja; Gross, Rüdiger; Jung, Christoph; Kiene, Miriam; Jacob, Timo; Pöhlmann, Stefan; Forssmann, Wolf-Georg; Münch, Jan; Sparrer, Konstantin M J; Seuwen, Klaus; Hahn, Beatrice H; Kirchhoff, Frank.
Afiliación
  • Hayn M; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Blötz A; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Rodríguez A; Core Facility Functional Peptidomics, Ulm University Medical Center, 89081 Ulm, Germany.
  • Vidal S; Core Unit Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081 Ulm, Germany.
  • Preising N; PHARIS Biotec GmbH, 30625 Hannover, Germany.
  • Ständker L; Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Wiese S; Core Facility Functional Peptidomics, Ulm University Medical Center, 89081 Ulm, Germany.
  • Stürzel CM; Core Facility Functional Peptidomics, Ulm University Medical Center, 89081 Ulm, Germany.
  • Harms M; Core Unit Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081 Ulm, Germany.
  • Gross R; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Jung C; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Kiene M; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Jacob T; Institute of Electrochemistry, Ulm University, 89081 Ulm, Germany.
  • Pöhlmann S; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.
  • Forssmann WG; Institute of Electrochemistry, Ulm University, 89081 Ulm, Germany.
  • Münch J; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.
  • Sparrer KMJ; Faculty of Biology and Psychology, University Göttingen, 37073 Göttingen, Germany.
  • Seuwen K; PHARIS Biotec GmbH, 30625 Hannover, Germany.
  • Hahn BH; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Kirchhoff F; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
Proc Natl Acad Sci U S A ; 118(3)2021 01 19.
Article en En | MEDLINE | ID: mdl-33431697
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / Síndrome de Inmunodeficiencia Adquirida del Simio / Receptores de Péptidos / Receptores Acoplados a Proteínas G / Cistatina C Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / Síndrome de Inmunodeficiencia Adquirida del Simio / Receptores de Péptidos / Receptores Acoplados a Proteínas G / Cistatina C Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article País de afiliación: Alemania