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Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease.
Dennis, Jessica K; Sealock, Julia M; Straub, Peter; Lee, Younga H; Hucks, Donald; Actkins, Ky'Era; Faucon, Annika; Feng, Yen-Chen Anne; Ge, Tian; Goleva, Slavina B; Niarchou, Maria; Singh, Kritika; Morley, Theodore; Smoller, Jordan W; Ruderfer, Douglas M; Mosley, Jonathan D; Chen, Guanhua; Davis, Lea K.
Afiliación
  • Dennis JK; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Sealock JM; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Straub P; Department of Medical Genetics, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.
  • Lee YH; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Hucks D; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Actkins K; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Faucon A; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Feng YA; Psychiatric & Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
  • Ge T; Department of Psychiatry, Harvard Medical School, Boston, MA, 02115, USA.
  • Goleva SB; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.
  • Niarchou M; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Singh K; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Morley T; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Smoller JW; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Ruderfer DM; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, 37232, USA.
  • Mosley JD; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Chen G; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Davis LK; Psychiatric & Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
Genome Med ; 13(1): 6, 2021 01 13.
Article en En | MEDLINE | ID: mdl-33441150
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biomarcadores / Enfermedad / Técnicas de Laboratorio Clínico / Herencia Multifactorial Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Genome Med Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biomarcadores / Enfermedad / Técnicas de Laboratorio Clínico / Herencia Multifactorial Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Genome Med Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos