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Establishment and characterization of induced pluripotent stem cell (iPSCs) line UNIBSi014-A from a healthy female donor.
Bono, Federica; Mutti, Veronica; Piovani, Giovanna; Minelli, Alessandra; Mingardi, Jessica; Guglielmi, Adele; Missale, Cristina; Gennarelli, Massimo; Fiorentini, Chiara; Barbon, Alessandro.
Afiliación
  • Bono F; Division of Pharmacology, Department of, Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
  • Mutti V; Division of Pharmacology, Department of, Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
  • Piovani G; Division of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
  • Minelli A; Division of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy; Genetic Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
  • Mingardi J; Division of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
  • Guglielmi A; Division of Pharmacology, Department of, Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
  • Missale C; Division of Pharmacology, Department of, Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
  • Gennarelli M; Division of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy; Genetic Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
  • Fiorentini C; Division of Pharmacology, Department of, Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy. Electronic address: chiara.fiorentini@unibs.it.
  • Barbon A; Division of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Stem Cell Res ; 51: 102216, 2021 03.
Article en En | MEDLINE | ID: mdl-33548809
ABSTRACT
Peripheral blood mononuclear cells (PBMCs) derived from a healthy 40-year-old female were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The resulting iPSCs line exhibits a normal karyotype, expresses stemness markers and displays the differentiation capacity into the three germ layers. This human iPSCs line can be used as healthy control in disease modelling studies.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas Límite: Adult / Female / Humans Idioma: En Revista: Stem Cell Res Año: 2021 Tipo del documento: Article País de afiliación: Italia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas Límite: Adult / Female / Humans Idioma: En Revista: Stem Cell Res Año: 2021 Tipo del documento: Article País de afiliación: Italia