Fam83D promotes tumorigenesis and gemcitabine resistance of pancreatic adenocarcinoma through the Wnt/ß-catenin pathway.

Hua, Yong-Qiang; Zhang, Ke; Sheng, Jie; Ning, Zhou-Yu; Li, Ye; Shi, Wei-Dong; Liu, Lu-Ming

Hua, Yong-Qiang; Zhang, Ke; Sheng, Jie; Ning, Zhou-Yu; Li, Ye; Shi, Wei-Dong; Liu, Lu-Ming.

Afiliación

Hua YQ; Minimally Invasive Treatment Center, Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai 200032, PR China; Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong An Road, Shanghai 200032, PR China.
Zhang K; Minimally Invasive Treatment Center, Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai 200032, PR China; Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong An Road, Shanghai 200032, PR China.
Sheng J; Minimally Invasive Treatment Center, Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai 200032, PR China; Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong An Road, Shanghai 200032, PR China.
Ning ZY; Minimally Invasive Treatment Center, Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai 200032, PR China; Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong An Road, Shanghai 200032, PR China.
Li Y; Minimally Invasive Treatment Center, Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai 200032, PR China; Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong An Road, Shanghai 200032, PR China.
Shi WD; Minimally Invasive Treatment Center, Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai 200032, PR China.
Liu LM; Minimally Invasive Treatment Center, Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai 200032, PR China; Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong An Road, Shanghai 200032, PR China. Electronic address: liuluming2018@163.com.

Life Sci ; 287: 119205, 2021 Dec 15.

Article en En | MEDLINE | ID: mdl-33571515

Asunto(s)

Adenocarcinoma/metabolismo; Carcinogénesis/metabolismo; Proteínas de Ciclo Celular/biosíntesis; Desoxicitidina/análogos & derivados; Proteínas Asociadas a Microtúbulos/biosíntesis; Neoplasias Pancreáticas/metabolismo; Vía de Señalización Wnt/fisiología; Adenocarcinoma/tratamiento farmacológico; Anciano; Animales; Carcinogénesis/efectos de los fármacos; Desoxicitidina/farmacología; Desoxicitidina/uso terapéutico; Resistencia a Antineoplásicos/efectos de los fármacos; Resistencia a Antineoplásicos/fisiología; Femenino; Humanos; Masculino; Ratones; Ratones Desnudos; Persona de Mediana Edad; Neoplasias Pancreáticas/tratamiento farmacológico; Vía de Señalización Wnt/efectos de los fármacos; Ensayos Antitumor por Modelo de Xenoinjerto/métodos; Gemcitabina

Palabras clave

Chemoresistance; Fam83D; Glycolysis; Pancreatic adenocarcinoma; ß-Catenin

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Adenocarcinoma / Proteínas de Ciclo Celular / Desoxicitidina / Vía de Señalización Wnt / Carcinogénesis / Proteínas Asociadas a Microtúbulos Límite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Life Sci Año: 2021 Tipo del documento: Article

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