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Human progranulin-expressing mice as a novel tool for the development of progranulin-modulating therapeutics.
Petkau, Terri L; Life, Benjamin; Lu, Ge; Yang, Jasmine; Fornes, Oriol; Wasserman, Wyeth; Simpson, Elizabeth M; Leavitt, Blair R.
Afiliación
  • Petkau TL; Centre for Molecular Medicine & Therapeutics, Department of Medical Genetics, University of British Columbia, B.C. Children's Hospital, 950 West 28(th) Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Life B; Centre for Molecular Medicine & Therapeutics, Department of Medical Genetics, University of British Columbia, B.C. Children's Hospital, 950 West 28(th) Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Lu G; Centre for Molecular Medicine & Therapeutics, Department of Medical Genetics, University of British Columbia, B.C. Children's Hospital, 950 West 28(th) Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Yang J; Centre for Molecular Medicine & Therapeutics, Department of Medical Genetics, University of British Columbia, B.C. Children's Hospital, 950 West 28(th) Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Fornes O; Centre for Molecular Medicine & Therapeutics, Department of Medical Genetics, University of British Columbia, B.C. Children's Hospital, 950 West 28(th) Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Wasserman W; Centre for Molecular Medicine & Therapeutics, Department of Medical Genetics, University of British Columbia, B.C. Children's Hospital, 950 West 28(th) Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Simpson EM; Centre for Molecular Medicine & Therapeutics, Department of Medical Genetics, University of British Columbia, B.C. Children's Hospital, 950 West 28(th) Avenue, Vancouver, BC V5Z 4H4, Canada; Center for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Leavitt BR; Centre for Molecular Medicine & Therapeutics, Department of Medical Genetics, University of British Columbia, B.C. Children's Hospital, 950 West 28(th) Avenue, Vancouver, BC V5Z 4H4, Canada; Division of Neurology, Department of Medicine, University of British Columbia Hospital, S 192 - 2211 Wesb
Neurobiol Dis ; 153: 105314, 2021 06.
Article en En | MEDLINE | ID: mdl-33636385
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Expresión Génica / Oligonucleótidos Antisentido / Demencia Frontotemporal / Progranulinas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Expresión Génica / Oligonucleótidos Antisentido / Demencia Frontotemporal / Progranulinas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Canadá