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Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor.
Willard, Francis S; Wainscott, David B; Showalter, Aaron D; Stutsman, Cynthia; Ma, Wenzhen; Cardona, Guemalli R; Zink, Richard W; Corkins, Christopher M; Chen, Qi; Yumibe, Nathan; Agejas, Javier; Cumming, Graham R; Minguez, José Miguel; Jiménez, Alma; Mateo, Ana I; Castaño, Ana M; Briere, Daniel A; Sloop, Kyle W; Bueno, Ana B.
Afiliación
  • Willard FS; Discovery Chemistry Research and Technologies, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Wainscott DB; Discovery Chemistry Research and Technologies, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Showalter AD; Diabetes and Complications, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Stutsman C; Diabetes and Complications, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Ma W; Diabetes and Complications, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Cardona GR; Discovery Chemistry Research and Technologies, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Zink RW; Discovery Chemistry Research and Technologies, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Corkins CM; Discovery Chemistry Research and Technologies, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Chen Q; Discovery Chemistry Research and Technologies, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Yumibe N; Investigative Drug Disposition, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Agejas J; Discovery Chemistry Research and Technologies, Lilly, S.A., Avda. de la Industria 30, Alcobendas, Madrid 28108, Spain.
  • Cumming GR; Discovery Chemistry Research and Technologies, Lilly, S.A., Avda. de la Industria 30, Alcobendas, Madrid 28108, Spain.
  • Minguez JM; Discovery Chemistry Research and Technologies, Lilly, S.A., Avda. de la Industria 30, Alcobendas, Madrid 28108, Spain.
  • Jiménez A; Discovery Chemistry Research and Technologies, Lilly, S.A., Avda. de la Industria 30, Alcobendas, Madrid 28108, Spain.
  • Mateo AI; Discovery Chemistry Research and Technologies, Lilly, S.A., Avda. de la Industria 30, Alcobendas, Madrid 28108, Spain.
  • Castaño AM; Discovery Chemistry Research and Technologies, Lilly, S.A., Avda. de la Industria 30, Alcobendas, Madrid 28108, Spain.
  • Briere DA; Diabetes and Complications, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Sloop KW; Diabetes and Complications, Lilly Research Laboratories, Indianapolis, Indiana 46285, United States.
  • Bueno AB; Discovery Chemistry Research and Technologies, Lilly, S.A., Avda. de la Industria 30, Alcobendas, Madrid 28108, Spain.
J Med Chem ; 64(6): 3439-3448, 2021 03 25.
Article en En | MEDLINE | ID: mdl-33721487
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación Alostérica / Receptor del Péptido 1 Similar al Glucagón / Hipoglucemiantes Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación Alostérica / Receptor del Péptido 1 Similar al Glucagón / Hipoglucemiantes Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos