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In vitro chronic glycation induces AGEs accumulation reducing insulin-stimulated glucose uptake and increasing GLP1R in adipocytes.
Chilelli, Nino-Cristiano; Faggian, Alessia; Favaretto, Francesca; Milan, Gabriella; Compagnin, Chiara; Dassie, Francesca; Bettini, Silvia; Roverso, Marco; Seraglia, Roberta; Lapolla, Annunziata; Vettor, Roberto.
Afiliación
  • Chilelli NC; Department of Medicine, University of Padua, Diabetology and Dietetics, Padua, Italy.
  • Faggian A; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Favaretto F; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Milan G; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Compagnin C; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Dassie F; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Bettini S; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Roverso M; Department of Chemical Sciences, University of Padua, Padua, Italy.
  • Seraglia R; Consiglio Nazionale delle Ricerche-Istituto di Chimica della Materia Condensata e di Tecnologie per l'Energia (CNR-ICMATE), Padua, Italy.
  • Lapolla A; Department of Medicine, University of Padua, Diabetology and Dietetics, Padua, Italy.
  • Vettor R; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
Am J Physiol Endocrinol Metab ; 320(5): E976-E988, 2021 05 01.
Article en En | MEDLINE | ID: mdl-33779307
ABSTRACT
Intracellular AGEs accumulation increases RAGE and GLP1R and reduces glucose uptake in adipocytes.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Productos Finales de Glicación Avanzada / Adipocitos / Receptor del Péptido 1 Similar al Glucagón / Glucosa / Insulina Límite: Animals / Humans Idioma: En Revista: Am J Physiol Endocrinol Metab Asunto de la revista: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Año: 2021 Tipo del documento: Article País de afiliación: Italia
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Productos Finales de Glicación Avanzada / Adipocitos / Receptor del Péptido 1 Similar al Glucagón / Glucosa / Insulina Límite: Animals / Humans Idioma: En Revista: Am J Physiol Endocrinol Metab Asunto de la revista: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Año: 2021 Tipo del documento: Article País de afiliación: Italia