Aspirin facilitates trophoblast invasion and epithelial-mesenchymal transition by regulating the miR-200-ZEB1 axis in preeclampsia.

Su, Mei-Tsz; Tsai, Pei-Yin; Wang, Chia-Yih; Tsai, Hui-Ling; Kuo, Pao-Lin

Su, Mei-Tsz; Tsai, Pei-Yin; Wang, Chia-Yih; Tsai, Hui-Ling; Kuo, Pao-Lin.

Afiliación

Su MT; Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 704, Taiwan; Department of Obstetrics and Gynecology, Tainan Hospital, Ministry of Health and Welfare, Tainan, Taiwan. Electronic address:
Tsai PY; Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 704, Taiwan.
Wang CY; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Tsai HL; Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 704, Taiwan.
Kuo PL; Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 704, Taiwan.

Biomed Pharmacother ; 139: 111591, 2021 Jul.

Article en En | MEDLINE | ID: mdl-33865015

Asunto(s)

Aspirina/farmacología; MicroARNs; Preeclampsia/genética; Preeclampsia/metabolismo; Factor de Crecimiento Transformador beta1/metabolismo; Trofoblastos/efectos de los fármacos; Homeobox 1 de Unión a la E-Box con Dedos de Zinc/metabolismo; Adulto; Antígenos CD/metabolismo; Cadherinas/metabolismo; Línea Celular; Movimiento Celular/efectos de los fármacos; Proliferación Celular; Transición Epitelial-Mesenquimal/efectos de los fármacos; Femenino; Humanos; Embarazo; Trofoblastos/metabolismo; Proteína de la Zonula Occludens-1/metabolismo

Palabras clave

Aspirin; Epithelial-mesenchymal transition; MiR-200; Preeclampsia; Trophoblast invasion

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Preeclampsia / Trofoblastos / Aspirina / MicroARNs / Factor de Crecimiento Transformador beta1 / Homeobox 1 de Unión a la E-Box con Dedos de Zinc Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Biomed Pharmacother Año: 2021 Tipo del documento: Article

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