Vitamin B3 levels in women who experience first-trimester miscarriage.
Aust N Z J Obstet Gynaecol
; 61(3): 478-483, 2021 06.
Article
en En
| MEDLINE
| ID: mdl-33866568
ABSTRACT
Miscarriage is the most common complication in early pregnancy. It was recently reported in mice that miscarriage can be prevented through the administration of niacin. We conducted a prospective, exploratory pilot study involving 24 women who were less than 14 weeks pregnant. Neither niacin intake (P = 0.24) nor urinary vitamin B3 measured as the 1-methyl-5-carboxylamide-2-pyridone/N-1-methylnicotinamide (2-pyr/MNA) ratio (P = 1.00) predicted miscarriage. However, the difference in mean 2-pyr/MNA ratios between women who miscarried and controls suggests there may be a threshold niacin level protective in miscarriage prevention warranting further investigation.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Aborto Espontáneo
/
Niacina
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Animals
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Aust N Z J Obstet Gynaecol
Año:
2021
Tipo del documento:
Article
País de afiliación:
Australia