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A Phase 1 dose-escalation study of disulfiram and copper gluconate in patients with advanced solid tumors involving the liver using S-glutathionylation as a biomarker.
Kelley, Kristen C; Grossman, Kenneth F; Brittain-Blankenship, Mary; Thorne, Kelli M; Akerley, Wallace L; Terrazas, Moises C; Kosak, Ken M; Boucher, Kenneth M; Buys, Saundra S; McGregor, Kimberly A; Werner, Theresa L; Agarwal, Neeraj; Weis, John R; Sharma, Sunil; Ward, John H; Kennedy, Thomas P; Sborov, Douglas W; Shami, Paul J.
Afiliación
  • Kelley KC; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
  • Grossman KF; Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • Brittain-Blankenship M; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
  • Thorne KM; Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • Akerley WL; Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • Terrazas MC; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, Utah, USA.
  • Kosak KM; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, Utah, USA.
  • Boucher KM; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
  • Buys SS; Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • McGregor KA; Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • Werner TL; Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • Agarwal N; Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • Weis JR; Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • Sharma S; Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • Ward JH; Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
  • Kennedy TP; Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University, New Orleans, USA.
  • Sborov DW; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, Utah, USA.
  • Shami PJ; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, Utah, USA. paul.shami@utah.edu.
BMC Cancer ; 21(1): 510, 2021 May 07.
Article en En | MEDLINE | ID: mdl-33957901
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Disulfiram / Gluconatos / Glutatión / Neoplasias Hepáticas / Neoplasias Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Disulfiram / Gluconatos / Glutatión / Neoplasias Hepáticas / Neoplasias Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos