Mechanisms of selective G protein-coupled receptor localization and trafficking.
Curr Opin Cell Biol
; 71: 158-165, 2021 08.
Article
en En
| MEDLINE
| ID: mdl-33965654
ABSTRACT
The trafficking of G protein-coupled receptors (GPCRs) to different membrane compartments has recently emerged as being a critical determinant of the signaling profiles of activation. GPCRs, which share many structural and functional similarities, also share many mechanisms that traffic them between compartments. This sharing raises the question of how the trafficking of individual GPCRs is selectively regulated. Here, we will discuss recent studies addressing the mechanisms that contribute to selectivity in endocytic and biosynthetic trafficking of GPCRs.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Transducción de Señal
/
Receptores Acoplados a Proteínas G
Idioma:
En
Revista:
Curr Opin Cell Biol
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos