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Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes.
Pazoki, Raha; Vujkovic, Marijana; Elliott, Joshua; Evangelou, Evangelos; Gill, Dipender; Ghanbari, Mohsen; van der Most, Peter J; Pinto, Rui Climaco; Wielscher, Matthias; Farlik, Matthias; Zuber, Verena; de Knegt, Robert J; Snieder, Harold; Uitterlinden, André G; Lynch, Julie A; Jiang, Xiyun; Said, Saredo; Kaplan, David E; Lee, Kyung Min; Serper, Marina; Carr, Rotonya M; Tsao, Philip S; Atkinson, Stephen R; Dehghan, Abbas; Tzoulaki, Ioanna; Ikram, M Arfan; Herzig, Karl-Heinz; Järvelin, Marjo-Riitta; Alizadeh, Behrooz Z; O'Donnell, Christopher J; Saleheen, Danish; Voight, Benjamin F; Chang, Kyong-Mi; Thursz, Mark R; Elliott, Paul.
Afiliación
  • Pazoki R; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, London, UK. raha.pazoki@brunel.ac.uk.
  • Vujkovic M; Division of Biomedical Sciences, Department of Life Sciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, UK. raha.pazoki@brunel.ac.uk.
  • Elliott J; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.
  • Evangelou E; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Gill D; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, London, UK.
  • Ghanbari M; Royal Surrey County Hospital, Guildford, Surrey, UK.
  • van der Most PJ; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, London, UK.
  • Pinto RC; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
  • Wielscher M; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, London, UK.
  • Farlik M; British Heart Foundation Centre of Research Excellence, Imperial College London, London, UK.
  • Zuber V; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
  • de Knegt RJ; Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • Uitterlinden AG; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, London, UK.
  • Lynch JA; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, London, UK.
  • Jiang X; Department of Dermatology, Medical University of Vienna, Vienna, Austria.
  • Said S; Department of Dermatology, Medical University of Vienna, Vienna, Austria.
  • Kaplan DE; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, London, UK.
  • Lee KM; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
  • Serper M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • Carr RM; Department of Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
  • Atkinson SR; VA Salt Lake City Health Care System, Salt Lake City, UT, USA.
  • Dehghan A; University of Massachusetts, Boston, MA, USA.
  • Tzoulaki I; Division of Biomedical Sciences, Department of Life Sciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, UK.
  • Ikram MA; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, London, UK.
  • Herzig KH; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.
  • Järvelin MR; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Alizadeh BZ; VA Salt Lake City Health Care System, Salt Lake City, UT, USA.
  • O'Donnell CJ; School of Medicine, University of Utah, Salt Lake City, UT, USA.
  • Saleheen D; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.
  • Voight BF; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Chang KM; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.
  • Thursz MR; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Elliott P; VA Palo Alto Health Care System, Palo Alto, CA, USA.
Nat Commun ; 12(1): 2579, 2021 05 10.
Article en En | MEDLINE | ID: mdl-33972514
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Alanina Transaminasa / Fosfatasa Alcalina / Gamma-Glutamiltransferasa / Hígado / Enfermedades Metabólicas Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Alanina Transaminasa / Fosfatasa Alcalina / Gamma-Glutamiltransferasa / Hígado / Enfermedades Metabólicas Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido