Targeted pH switched europium complexes monitoring receptor internalisation in living cells.
Chem Commun (Camb)
; 57(47): 5814-5817, 2021 Jun 10.
Article
en En
| MEDLINE
| ID: mdl-34002181
ABSTRACT
We report the design and evaluation of pH responsive luminescent europium(iii) probes that allow conjugation to targeting vectors to monitor receptor internalisation in cells. The approach adopted here can be used to tag proteins selectively and to monitor uptake into more acidic organelles, thereby enhancing the performance of time-resolved internalisation assays that require pH monitoring in real time.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sustancias Luminiscentes
/
Europio
/
Complejos de Coordinación
/
Receptor del Péptido 1 Similar al Glucagón
Límite:
Humans
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Reino Unido