Selective Inhibition of DNA Polymerase ß by a Covalent Inhibitor.

Yuhas, Shelby C; Laverty, Daniel J; Lee, Huijin; Majumdar, Ananya; Greenberg, Marc M

Yuhas, Shelby C; Laverty, Daniel J; Lee, Huijin; Majumdar, Ananya; Greenberg, Marc M.

Afiliación

Yuhas SC; Johns Hopkins University, Department of Chemistry, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
Laverty DJ; Johns Hopkins University, Department of Chemistry, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
Lee H; Johns Hopkins University, Department of Chemistry, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
Majumdar A; Johns Hopkins University, Biomolecular NMR Center, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
Greenberg MM; Johns Hopkins University, Department of Chemistry, 3400 North Charles Street, Baltimore, Maryland 21218, United States.

J Am Chem Soc ; 143(21): 8099-8107, 2021 06 02.

Article en En | MEDLINE | ID: mdl-34014094

Asunto(s)

ADN Polimerasa beta/antagonistas & inhibidores; Inhibidores Enzimáticos/farmacología; Animales; ADN Polimerasa beta/metabolismo; Inhibidores Enzimáticos/química; Fibroblastos/enzimología; Células HeLa; Humanos; Ratones

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN Polimerasa beta / Inhibidores Enzimáticos Límite: Animals / Humans Idioma: En Revista: J Am Chem Soc Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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