The Genitourinary Pathology Society Update on Classification of Variant Histologies, T1 Substaging, Molecular Taxonomy, and Immunotherapy and PD-L1 Testing Implications of Urothelial Cancers.
Adv Anat Pathol
; 28(4): 196-208, 2021 07 01.
Article
en En
| MEDLINE
| ID: mdl-34128484
ABSTRACT
The Genitourinary Pathology Society (GUPS) undertook a critical review of the recent advances in bladder cancer focusing on important topics of high interest for the practicing surgical pathologist and urologist. This review represents the second of 2 manuscripts ensuing from this effort. Herein, we address the effective reporting of bladder cancer, focusing particularly on newly published data since the last 2016 World Health Organization (WHO) classification. In addition, this review focuses on the importance of reporting bladder cancer with divergent differentiation and variant (subtypes of urothelial carcinoma) histologies and the potential impact on patient care. We provide new recommendations for reporting pT1 staging in diagnostic pathology. Furthermore, we explore molecular evolution and classification, emphasizing aspects that impact the understanding of important concepts relevant to reporting and management of patients.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Carcinoma de Células Transicionales
/
Neoplasias Urológicas
/
Inmunoterapia
Tipo de estudio:
Guideline
Límite:
Humans
Idioma:
En
Revista:
Adv Anat Pathol
Asunto de la revista:
ANATOMIA
/
PATOLOGIA
Año:
2021
Tipo del documento:
Article