Examining feedback mechanisms of postural control in Chiari Malformation by average wavelet coefficient decomposition and the Hurst exponent.
Gait Posture
; 88: 280-285, 2021 07.
Article
en En
| MEDLINE
| ID: mdl-34153805
ABSTRACT
BACKGROUND:
Chiari Malformation (CM) is a congenital disorder occurring when the cerebellar tonsils descend into the foramen magnum, inhibiting cerebrospinal fluid (CSF) flow, causing headaches, dizziness, difficulty swallowing, muscle weakness, and loss of neuromuscular coordination. While there is no cure, surgical decompression of the hindbrain is used to alleviate symptoms. Loss of postural control is a main symptom reported by these patients; however, no study has examined postural stability in this cohort of patients. RESEARCH QUESTION Do patients with CM exhibit impaired postural stability compared to healthy controls?.METHODS:
Twelve female participants diagnosed with CM performed a postural stability test where six participants had undergone decompression (CM-D) surgery while six had not (CM-ND). Participants stood in Romberg fashion on an AMTI force plate according to an IRB-approved protocol. Postural stability measures were quantified by computing Hurst exponents. These values were determined from the Average Wavelet Coefficient method using a level 12 Symlet-2 wavelet to analyze anterior-posterior (AP) center-ofpressure (COP) trajectories in MATLAB. Identical procedures and analyses were performed on healthy control participants with no known neuromuscular disorders.RESULTS:
CM participants displayed significantly impaired postural stability compared to healthy controls (p = 0.0002). CM-D participants displayed significantly impaired postural stability compared to CM-ND (p = 0.002). CM-D and CM-ND both displayed significantly impaired postural stability compared to controls (p < 0.0001 and p < 0.003, respectively).SIGNIFICANCE:
Loss of postural stability is considered a main symptom of CM, however no study has previously quantified human postural control in this cohort of patients. Quantifying this relationship can provide further insight to neurologists studying the disorder and to therapists planning rehabilitation and pain relief methods.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Malformación de Arnold-Chiari
/
Siringomielia
Tipo de estudio:
Guideline
Límite:
Female
/
Humans
Idioma:
En
Revista:
Gait Posture
Asunto de la revista:
ORTOPEDIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos