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The role and uses of antibodies in COVID-19 infections: a living review.
Scourfield, D Oliver; Reed, Sophie G; Quastel, Max; Alderson, Jennifer; Bart, Valentina M T; Teijeira Crespo, Alicia; Jones, Ruth; Pring, Ellie; Richter, Felix Clemens; Burnell, Stephanie E A.
Afiliación
  • Scourfield DO; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
  • Reed SG; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
  • Quastel M; Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
  • Alderson J; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, OX3 FTY, UK.
  • Bart VMT; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
  • Teijeira Crespo A; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, CF14 4XN UK.
  • Jones R; Dementia Research Institute, Cardiff University, Cardiff, CF24 4HQ, UK.
  • Pring E; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
  • Richter FC; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, OX3 FTY, UK.
  • Burnell SEA; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
Oxf Open Immunol ; 2(1): iqab003, 2021.
Article en En | MEDLINE | ID: mdl-34192270
Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Oxf Open Immunol Año: 2021 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Oxf Open Immunol Año: 2021 Tipo del documento: Article