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Neural stem cell delivery of an oncolytic adenovirus in newly diagnosed malignant glioma: a first-in-human, phase 1, dose-escalation trial.
Fares, Jawad; Ahmed, Atique U; Ulasov, Ilya V; Sonabend, Adam M; Miska, Jason; Lee-Chang, Catalina; Balyasnikova, Irina V; Chandler, James P; Portnow, Jana; Tate, Matthew C; Kumthekar, Priya; Lukas, Rimas V; Grimm, Sean A; Adams, Ann K; Hébert, Charles D; Strong, Theresa V; Amidei, Christina; Arrieta, Victor A; Zannikou, Markella; Horbinski, Craig; Zhang, Hui; Burdett, Kirsten Bell; Curiel, David T; Sachdev, Sean; Aboody, Karen S; Stupp, Roger; Lesniak, Maciej S.
Afiliación
  • Fares J; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Ahmed AU; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Ulasov IV; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Sonabend AM; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Miska J; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Lee-Chang C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Balyasnikova IV; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Chandler JP; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Portnow J; Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, CA.
  • Tate MC; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Kumthekar P; Department of Neurology, Division of Neuro-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Lukas RV; Department of Neurology, Division of Neuro-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Grimm SA; Department of Neurology, Division of Neuro-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Adams AK; Office of the Vice-President for Research, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Hébert CD; Southern Research Institute, Birmingham, AL, USA.
  • Strong TV; Foundation for Prader-Willi Research, Walnut, CA, USA.
  • Amidei C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Arrieta VA; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Zannikou M; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Horbinski C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Department of Pathology, Division of Neuropathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Zhang H; Department of Preventive Medicine, Division of Biostatistics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Burdett KB; Department of Preventive Medicine, Division of Biostatistics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Curiel DT; Department of Radiation Oncology, Washington University School of Medicine in Saint Louis, MO, USA.
  • Sachdev S; Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Aboody KS; Department of Developmental & Stem Cell Biology, Division of Neurosurgery, City of Hope, Duarte, CA.
  • Stupp R; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Lesniak MS; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address: maciej.lesniak@northwestern.edu.
Lancet Oncol ; 22(8): 1103-1114, 2021 08.
Article en En | MEDLINE | ID: mdl-34214495
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Viroterapia Oncolítica / Células-Madre Neurales / Glioma Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Viroterapia Oncolítica / Células-Madre Neurales / Glioma Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos