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Single-stage long-segment tracheal transplantation.
Genden, Eric M; Miles, Brett A; Harkin, Timothy J; DeMaria, Samuel; Kaufman, Andrew J; Mayland, Erica; Kaul, Vivian F; Florman, Sander S.
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  • Genden EM; Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Miles BA; The Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Harkin TJ; Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • DeMaria S; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Kaufman AJ; Department of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Mayland E; Department of Anesthesia, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Kaul VF; Department of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Florman SS; Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Am J Transplant ; 21(10): 3421-3427, 2021 10.
Article en En | MEDLINE | ID: mdl-34236746
ABSTRACT
Tracheal transplantation has been envisioned as a viable option for reconstruction of long-segment tracheal defects. We report the first human single-stage long-segment tracheal transplantation. Narrow-band imaging and bronchoscopic biopsies demonstrate allograft vascularization and viable epithelial lining. The recipient was immunosuppressed with Tacrolimus, Mycophenolate mofetil, and corticosteroids. Six months after transplantation, the trachea is both functional and the patient is breathing without the need of a tracheostomy or stent.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tráquea / Procedimientos de Cirugía Plástica Límite: Humans Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tráquea / Procedimientos de Cirugía Plástica Límite: Humans Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos