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Ca2+/calmodulin-dependent Protein Kinases in Leukemia Development.
Cui, Changhao; Wang, Chen; Cao, Min; Kang, Xunlei.
Afiliación
  • Cui C; School of Life Science and Medicine, Dalian University of Technology, Liaoning 124221, China.
  • Wang C; Center for Precision Medicine, Department of Medicine, University of Missouri, 1 Hospital Drive, Columbia, Missouri 65212, USA.
  • Cao M; Center for Precision Medicine, Department of Medicine, University of Missouri, 1 Hospital Drive, Columbia, Missouri 65212, USA.
  • Kang X; Center for Precision Medicine, Department of Medicine, University of Missouri, 1 Hospital Drive, Columbia, Missouri 65212, USA.
J Cell Immunol ; 3(3): 144-150, 2021.
Article en En | MEDLINE | ID: mdl-34263253
ABSTRACT
Ca2+/calmodulin (CaM) signaling is important for a wide range of cellular functions. It is not surprised the role of this signaling has been recognized in tumor progressions, such as proliferation, invasion, and migration. However, its role in leukemia has not been well appreciated. The multifunctional Ca2+/CaM-dependent protein kinases (CaMKs) are critical intermediates of this signaling and play key roles in cancer development. The most investigated CaMKs in leukemia, especially myeloid leukemia, are CaMKI, CaMKII, and CaMKIV. The function and mechanism of these kinases in leukemia development are summarized in this study.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: J Cell Immunol Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: J Cell Immunol Año: 2021 Tipo del documento: Article País de afiliación: China