Chemo-, regio- and stereoselective synthesis of monofluoroalkenes via a tandem fluorination-desulfonation sequence.
Chem Commun (Camb)
; 57(63): 7802-7805, 2021 Aug 05.
Article
en En
| MEDLINE
| ID: mdl-34268540
ABSTRACT
A widely applicable approach for the synthesis of Z-monofluoroalkenes from readily available alkyl triflones and NFSI has been reported. The reaction proceeded under mild conditions, affording mono-fluorinated alkenes in good to excellent yields with excellent chemo- regio- and stereoselectivity. The mechanism may involve electrophilic fluorination of triflones followed by the highly stereoselective concerted bimolecular elimination (E2) of CF3SO2H.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Alquenos
/
Hidrocarburos Fluorados
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2021
Tipo del documento:
Article