Danshensu inhibits the IL-1ß-induced inflammatory response in chondrocytes and osteoarthritis possibly via suppressing NF-&#954;B signaling pathway.

Xu, Zhixian; Ke, Tie; Zhang, Yongfa; Guo, Licheng; Chen, Feng; He, Wubing

Danshensu inhibits the IL-1ß-induced inflammatory response in chondrocytes and osteoarthritis possibly via suppressing NF-κB signaling pathway.

Xu, Zhixian; Ke, Tie; Zhang, Yongfa; Guo, Licheng; Chen, Feng; He, Wubing.

Afiliación

Xu Z; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350004, Fujian Province, People's Republic of China.
Ke T; Department of Emergency Surgery, Fujian Provincial Hospital, No.134 East Street, Gulou District, Fuzhou, 350001, Fujian Province, People's Republic of China.
Zhang Y; Fujian Provincial Key Laboratory of Emergency Medicine, Fujian Provincial Hospital, Fuzhou, 350001, Fujian, People's Republic of China.
Guo L; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350004, Fujian Province, People's Republic of China.
Chen F; Department of Emergency Surgery, Fujian Provincial Hospital, No.134 East Street, Gulou District, Fuzhou, 350001, Fujian Province, People's Republic of China.
He W; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350004, Fujian Province, People's Republic of China.

Mol Med ; 27(1): 80, 2021 07 20.

Article en En | MEDLINE | ID: mdl-34284715

Asunto(s)

Condrocitos/efectos de los fármacos; Condrocitos/metabolismo; Interleucina-1beta/metabolismo; Lactatos/farmacología; FN-kappa B/metabolismo; Osteoartritis/metabolismo; Transducción de Señal/efectos de los fármacos; Animales; Biomarcadores; Supervivencia Celular/efectos de los fármacos; Citocinas/metabolismo; Modelos Animales de Enfermedad; Progresión de la Enfermedad; Susceptibilidad a Enfermedades; Matriz Extracelular/metabolismo; Mediadores de Inflamación/metabolismo; Lactatos/administración & dosificación; Lactatos/química; Ratones; Osteoartritis/tratamiento farmacológico; Osteoartritis/etiología; Osteoartritis/patología

Palabras clave

Danshensu; IL-1ß; Inflammatory response; NF-κB; Osteoarthritis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis / Transducción de Señal / FN-kappa B / Condrocitos / Interleucina-1beta / Lactatos Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article

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