Maternal Epilepsy and Umbilical Cord Blood Oxidative Stress Level.
Fetal Pediatr Pathol
; 41(5): 731-740, 2022 Oct.
Article
en En
| MEDLINE
| ID: mdl-34338603
ABSTRACT
INTRODUCTION:
We investigated the effect of epilepsy on cord blood oxidative stress status. MATERIAL ANDMETHODS:
Thirty (n = 30) pregnant women with epilepsy and thirty (n = 30) healthy controls enrolled in this case control study. Albumin and IMA values and dynamic thiol/disulfide parameters were measured.RESULTS:
Decreased native thiol and total thiol levels were found in the epilepsy group when compared to the control group (p 0.001, p 0.002). Higher IMA (p 0.036) and lower albumin cord levels (P < 0.001) were measured in the epilepsy group with respect to the control group. Apgar scores at 1 and 5 miutes were lower in the epilepsy group (respectively; p = 0.012, p = 0.010). A negative correlation was found between IMA and cord pH value (r = 0.288 p = 0.034).CONCLUSION:
This study showed that epilepsy may alter thiol disulfide homeostasis and IMA levels.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Epilepsia
/
Sangre Fetal
Tipo de estudio:
Observational_studies
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Fetal Pediatr Pathol
Asunto de la revista:
PATOLOGIA
/
PEDIATRIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Turquía