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Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases.
Cai, Na; Gomez-Duran, Aurora; Yonova-Doing, Ekaterina; Kundu, Kousik; Burgess, Annette I; Golder, Zoe J; Calabrese, Claudia; Bonder, Marc J; Camacho, Marta; Lawson, Rachael A; Li, Lixin; Williams-Gray, Caroline H; Di Angelantonio, Emanuele; Roberts, David J; Watkins, Nick A; Ouwehand, Willem H; Butterworth, Adam S; Stewart, Isobel D; Pietzner, Maik; Wareham, Nick J; Langenberg, Claudia; Danesh, John; Walter, Klaudia; Rothwell, Peter M; Howson, Joanna M M; Stegle, Oliver; Chinnery, Patrick F; Soranzo, Nicole.
Afiliación
  • Cai N; Human Genetics Department, Wellcome Sanger Institute (WT), Hinxton, UK.
  • Gomez-Duran A; European Bioinformatics Institute (EMBL-EBI), Hinxton, UK.
  • Yonova-Doing E; Helmholtz Pioneer Campus, Helmholtz Zentrum München, Neuherberg, Germany.
  • Kundu K; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
  • Burgess AI; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
  • Golder ZJ; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CIB-CSIC), Madrid, Spain.
  • Calabrese C; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Primary Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Bonder MJ; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK.
  • Camacho M; Human Genetics Department, Wellcome Sanger Institute (WT), Hinxton, UK.
  • Lawson RA; Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
  • Li L; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
  • Williams-Gray CH; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
  • Di Angelantonio E; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
  • Roberts DJ; European Bioinformatics Institute (EMBL-EBI), Hinxton, UK.
  • Watkins NA; Division of Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Ouwehand WH; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
  • Butterworth AS; Translational and Clinical Research Institute, Newcastle University, Newcastle, UK.
  • Stewart ID; Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
  • Pietzner M; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
  • Langenberg C; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Primary Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Danesh J; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.
  • Walter K; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.
  • Rothwell PM; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.
  • Howson JMM; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.
  • Stegle O; NHS Blood and Transplant-Oxford Centre, John Radcliffe Hospital, Oxford, UK.
  • Chinnery PF; Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Soranzo N; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.
Nat Med ; 27(9): 1564-1575, 2021 09.
Article en En | MEDLINE | ID: mdl-34426706
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN Mitocondrial / Biomarcadores / Enfermedades Cardiovasculares / Mitocondrias Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN Mitocondrial / Biomarcadores / Enfermedades Cardiovasculares / Mitocondrias Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2021 Tipo del documento: Article