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Novel selective κ agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion.
Wei, Yuan-Yuan; Ma, Yan; Yao, Song-Yu; Kong, Ling-Hui; Liu, Xiao; Chai, Jing-Rui; Chen, Jing; Li, Wei; Wang, Yu-Jun; Shao, Li-Ming; Liu, Jing-Gen.
Afiliación
  • Wei YY; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Ma Y; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Yao SY; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Kong LH; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Liu X; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
  • Chai JR; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China.
  • Chen J; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China.
  • Li W; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Wang YJ; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Shao LM; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China. wei-li@fudan.edu.cn.
  • Liu JG; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. yjwang@mail.simm.ac.cn.
Acta Pharmacol Sin ; 43(6): 1372-1382, 2022 Jun.
Article en En | MEDLINE | ID: mdl-34493813
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Opioides kappa / Antipruriginosos Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Opioides kappa / Antipruriginosos Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China