Deep learning trained on hematoxylin and eosin tumor region of Interest predicts HER2 status and trastuzumab treatment response in HER2+ breast cancer.

Farahmand, Saman; Fernandez, Aileen I; Ahmed, Fahad Shabbir; Rimm, David L; Chuang, Jeffrey H; Reisenbichler, Emily; Zarringhalam, Kourosh

Farahmand, Saman; Fernandez, Aileen I; Ahmed, Fahad Shabbir; Rimm, David L; Chuang, Jeffrey H; Reisenbichler, Emily; Zarringhalam, Kourosh.

Afiliación

Farahmand S; University of Massachusetts-Boston, Department of Mathematics, Boston, MA, USA.
Fernandez AI; University of Massachusetts-Boston, Computational Sciences PhD Program, Boston, MA, USA.
Ahmed FS; Yale University, Yale School of Medicine, Department of Pathology, New Haven, CT, USA.
Rimm DL; Yale University, Yale School of Medicine, Department of Pathology, New Haven, CT, USA.
Chuang JH; Yale University, Yale School of Medicine, Department of Pathology, New Haven, CT, USA.
Reisenbichler E; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. Jeff.Chuang@jax.org.
Zarringhalam K; UCONN Health, Department of Genetics and Genome Sciences, Farmington, CT, USA. Jeff.Chuang@jax.org.

Mod Pathol ; 35(1): 44-51, 2022 01.

Article en En | MEDLINE | ID: mdl-34493825

Asunto(s)

Antineoplásicos Inmunológicos/uso terapéutico; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/patología; Receptor ErbB-2/análisis; Trastuzumab/uso terapéutico; Área Bajo la Curva; Estudios de Cohortes; Femenino; Humanos; Curva ROC; Distribución Aleatoria; Receptor ErbB-2/genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptor ErbB-2 / Trastuzumab / Antineoplásicos Inmunológicos Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Mod Pathol Asunto de la revista: PATOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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