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Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.
Auffenberg, Eva; Hedrich, Ulrike Bs; Barbieri, Raffaella; Miely, Daniela; Groschup, Bernhard; Wuttke, Thomas V; Vogel, Niklas; Lührs, Philipp; Zanardi, Ilaria; Bertelli, Sara; Spielmann, Nadine; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Pusch, Michael; Dichgans, Martin; Lerche, Holger; Gavazzo, Paola; Plesnila, Nikolaus; Freilinger, Tobias.
Afiliación
  • Auffenberg E; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Hedrich UB; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
  • Barbieri R; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Miely D; Biophysics Institute, Consiglio Nazionale delle Ricerche (CNR), Genoa, Italy.
  • Groschup B; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Wuttke TV; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
  • Vogel N; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Lührs P; Department of Neurosurgery, University of Tübingen, Tübingen, Germany.
  • Zanardi I; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Bertelli S; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Spielmann N; Biophysics Institute, Consiglio Nazionale delle Ricerche (CNR), Genoa, Italy.
  • Gailus-Durner V; Biophysics Institute, Consiglio Nazionale delle Ricerche (CNR), Genoa, Italy.
  • Fuchs H; German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Hrabe de Angelis M; German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Pusch M; German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Dichgans M; German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Lerche H; Chair of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Freising, Germany.
  • Gavazzo P; German Center for Diabetes Research (DZD), Neuherberg, Germany.
  • Plesnila N; Biophysics Institute, Consiglio Nazionale delle Ricerche (CNR), Genoa, Italy.
  • Freilinger T; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
J Clin Invest ; 131(21)2021 11 01.
Article en En | MEDLINE | ID: mdl-34546973
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Depresión de Propagación Cortical / Canal de Sodio Activado por Voltaje NAV1.1 / Heterocigoto / Interneuronas / Trastornos Migrañosos / Mutación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Clin Invest Año: 2021 Tipo del documento: Article País de afiliación: Alemania
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Depresión de Propagación Cortical / Canal de Sodio Activado por Voltaje NAV1.1 / Heterocigoto / Interneuronas / Trastornos Migrañosos / Mutación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Clin Invest Año: 2021 Tipo del documento: Article País de afiliación: Alemania