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A Cryptic Plant Terpene Cyclase Producing Unconventional 18- and 14-Membered Macrocyclic C25 and C20 Terpenoids with Immunosuppressive Activity.
Chen, Yue-Gui; Li, De-Sen; Ling, Yi; Liu, Yan-Chun; Zuo, Zhi-Li; Gan, Li-She; Luo, Shi-Hong; Hua, Juan; Chen, Ding-Yuan; Xu, Fan; Li, Man; Guo, Kai; Liu, Yan; Gershenzon, Jonathan; Li, Sheng-Hong.
Afiliación
  • Chen YG; State Key Laboratory of Southwestern Chinese Medicine Resources, and, Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, P. R. China.
  • Li DS; State Key Laboratory of Phytochemistry and Plant Resources in West China &, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of, Sciences, Kunming, 650201, P. R. China.
  • Ling Y; University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
  • Liu YC; State Key Laboratory of Southwestern Chinese Medicine Resources, and, Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, P. R. China.
  • Zuo ZL; State Key Laboratory of Phytochemistry and Plant Resources in West China &, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of, Sciences, Kunming, 650201, P. R. China.
  • Gan LS; University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
  • Luo SH; State Key Laboratory of Phytochemistry and Plant Resources in West China &, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of, Sciences, Kunming, 650201, P. R. China.
  • Hua J; State Key Laboratory of Phytochemistry and Plant Resources in West China &, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of, Sciences, Kunming, 650201, P. R. China.
  • Chen DY; University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
  • Xu F; State Key Laboratory of Phytochemistry and Plant Resources in West China &, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of, Sciences, Kunming, 650201, P. R. China.
  • Li M; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, 529020, P. R. China.
  • Guo K; State Key Laboratory of Phytochemistry and Plant Resources in West China &, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of, Sciences, Kunming, 650201, P. R. China.
  • Liu Y; State Key Laboratory of Phytochemistry and Plant Resources in West China &, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of, Sciences, Kunming, 650201, P. R. China.
  • Gershenzon J; State Key Laboratory of Phytochemistry and Plant Resources in West China &, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of, Sciences, Kunming, 650201, P. R. China.
  • Li SH; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, 529020, P. R. China.
Angew Chem Int Ed Engl ; 60(48): 25468-25476, 2021 11 22.
Article en En | MEDLINE | ID: mdl-34580976
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Terpenos / Interferón gamma / Interleucina-2 / Transferasas Alquil y Aril / Compuestos Macrocíclicos / Inmunosupresores Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Terpenos / Interferón gamma / Interleucina-2 / Transferasas Alquil y Aril / Compuestos Macrocíclicos / Inmunosupresores Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article