Psychological impact of the COVID-19 pandemic for patients with epilepsy: A systematic review and meta-analysis.
Epilepsy Behav
; 124: 108340, 2021 Sep 29.
Article
en En
| MEDLINE
| ID: mdl-34600283
ABSTRACT
OBJECTIVE:
To investigate psychological comorbidities in patients with epilepsy during the coronavirus disease 2019 (COVID-19) pandemic.METHOD:
A systematic review and meta-analysis approach was used to comprehensively search MEDLINE, CENTRAL, EMBASE, and ClinicalTrials.gov databases for relevant studies. Studies that reported psychological stress in patients with epilepsy during the COVID-19 pandemic were included. Psychological comorbidities were defined as anxiety, depression, and sleep disturbance. Pooled proportions of psychological comorbidities with 95% confidence intervals (CIs) were assessed using a random-effects model. The quality of assessment for each study, heterogeneity between the studies, and publication bias were also evaluated.RESULTS:
A total of 28 studies with 7959 patients/caregivers were included in the meta-analysis. The pooled proportions of anxiety/worry, depression/bad mood, and sleep disturbance were 38.9% (95% CI 31.3-46.7); I2â¯=â¯97%; pâ¯<â¯0.01, 30.9% (95% CI 23.3-38.9), I2â¯=â¯97%; pâ¯<â¯0.01, and 36.5% (95% CI 28.3-45.1), I2â¯=â¯97%, pâ¯<â¯0.01, respectively.CONCLUSION:
Although the heterogeneity was high, our results showed a relatively high incidence of psychological comorbidities. Therefore, clinicians need to intervene early in the stress of patients with epilepsy to prevent worsening of stress, which can result in seizure worsening.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Tipo de estudio:
Systematic_reviews
Idioma:
En
Revista:
Epilepsy Behav
Asunto de la revista:
CIENCIAS DO COMPORTAMENTO
/
NEUROLOGIA
Año:
2021
Tipo del documento:
Article