Molecular Mechanisms of Sexually Dimorphic Nervous System Patterning in Flies and Worms.
Annu Rev Cell Dev Biol
; 37: 519-547, 2021 10 06.
Article
en En
| MEDLINE
| ID: mdl-34613817
ABSTRACT
Male and female brains display anatomical and functional differences. Such differences are observed in species across the animal kingdom, including humans, but have been particularly well-studied in two classic animal model systems, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans. Here we summarize recent advances in understanding how the worm and fly brain acquire sexually dimorphic features during development. We highlight the advantages of each system, illustrating how the precise anatomical delineation of sexual dimorphisms in worms has enabled recent analysis into how these dimorphisms become specified during development, and how focusing on sexually dimorphic neurons in the fly has enabled an increasingly detailed understanding of sex-specific behaviors.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Drosophila melanogaster
/
Sistema Nervioso
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Annu Rev Cell Dev Biol
Asunto de la revista:
BIOLOGIA
Año:
2021
Tipo del documento:
Article