A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa.
Science
; 374(6566): 423-431, 2021 Oct 22.
Article
en En
| MEDLINE
| ID: mdl-34672751
ABSTRACT
The progression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in Africa has so far been heterogeneous, and the full impact is not yet well understood. In this study, we describe the genomic epidemiology using a dataset of 8746 genomes from 33 African countries and two overseas territories. We show that the epidemics in most countries were initiated by importations predominantly from Europe, which diminished after the early introduction of international travel restrictions. As the pandemic progressed, ongoing transmission in many countries and increasing mobility led to the emergence and spread within the continent of many variants of concern and interest, such as B.1.351, B.1.525, A.23.1, and C.1.1. Although distorted by low sampling numbers and blind spots, the findings highlight that Africa must not be left behind in the global pandemic response, otherwise it could become a source for new variants.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Genómica
/
Pandemias
/
Monitoreo Epidemiológico
/
SARS-CoV-2
/
COVID-19
Tipo de estudio:
Screening_studies
Límite:
Humans
País/Región como asunto:
Africa
Idioma:
En
Revista:
Science
Año:
2021
Tipo del documento:
Article
País de afiliación:
Sudáfrica