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Paravalvular Aortic Regurgitation Severity Assessed by Quantitative Aortography: ACURATE neo2 versus ACURATE neo Transcatheter Aortic Valve Implantation.
Rück, Andreas; Kim, Won-Keun; Kawashima, Hideyuki; Abdelshafy, Mahmoud; Elkoumy, Ahmed; Elzomor, Hesham; Wang, Rutao; Meduri, Christopher U; Verouhis, Dinos; Saleh, Nawzad; Onuma, Yoshinobu; Mylotte, Darren; Serruys, Patrick W; Soliman, Osama.
Afiliación
  • Rück A; Department of Cardiology, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
  • Kim WK; Kerckhoff Heart Center, Department of Cardiology, 61231 Bad Nauheim, Germany.
  • Kawashima H; Discipline of Cardiology, Saolta Group, Galway University Hospital, Health Service Executive and CORRIB Core Lab, National University of Ireland Galway (NUIG), H91 V4AY Galway, Ireland.
  • Abdelshafy M; Academic Medical Centre, Department of Cardiology, University of Amsterdam, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands.
  • Elkoumy A; Discipline of Cardiology, Saolta Group, Galway University Hospital, Health Service Executive and CORRIB Core Lab, National University of Ireland Galway (NUIG), H91 V4AY Galway, Ireland.
  • Elzomor H; Discipline of Cardiology, Saolta Group, Galway University Hospital, Health Service Executive and CORRIB Core Lab, National University of Ireland Galway (NUIG), H91 V4AY Galway, Ireland.
  • Wang R; Discipline of Cardiology, Saolta Group, Galway University Hospital, Health Service Executive and CORRIB Core Lab, National University of Ireland Galway (NUIG), H91 V4AY Galway, Ireland.
  • Meduri CU; Discipline of Cardiology, Saolta Group, Galway University Hospital, Health Service Executive and CORRIB Core Lab, National University of Ireland Galway (NUIG), H91 V4AY Galway, Ireland.
  • Verouhis D; Department of Cardiology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
  • Saleh N; Department of Cardiology, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
  • Onuma Y; Department of Cardiology, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
  • Mylotte D; Department of Cardiology, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
  • Serruys PW; Discipline of Cardiology, Saolta Group, Galway University Hospital, Health Service Executive and CORRIB Core Lab, National University of Ireland Galway (NUIG), H91 V4AY Galway, Ireland.
  • Soliman O; Discipline of Cardiology, Saolta Group, Galway University Hospital, Health Service Executive and CORRIB Core Lab, National University of Ireland Galway (NUIG), H91 V4AY Galway, Ireland.
J Clin Med ; 10(20)2021 Oct 09.
Article en En | MEDLINE | ID: mdl-34682750
The new-generation ACURATE neo2 system was commercially released in September 2020. In this study, we sought to compare the aortic regurgitation (AR) severity of the ACURATE neo2 versus the ACURATE neo transcatheter heart valve, using quantitative videodensitometric angiography (qAR). This is a retrospective, Corelab analysis of final post-transcatheter aortic valve implantation (TAVI) aortograms of patients treated with the ACURATE neo2 and ACURATE neo systems. The ACURATE neo2 cohort comprised consecutive patients treated between September 2020 and January 2021 at two centers. The ACURATE neo cohort included consecutive patients treated before September 2020. Our primary objective was to compare AR severity on qAR following TAVI with ACURATE neo2 and ACURATE neo. Out of 401 aortograms, 228 (56.9%) were analyzable, with 120 in the ACURATE neo2 cohort, and 108 in the ACURATE neo cohort. The mean AR fraction was 4.4 ± 4.8% in the neo2 cohort, and 9.9 ± 8.2% in the neo cohort (p < 0.001). Furthermore, moderate or severe AR (qAR > 17%) was detected in 2 aortograms (1.7%) in the neo2 cohort and 15 aortograms (13.9%) in the neo cohort (p < 0.001). Quantitative aortography shows a lower rate of moderate or severe paravalvular AR in what is the first European experience of the new-generation, self-expanding ACURATE neo2 when compared to the first-generation ACURATE neo. Moreover, aortographic data need to be correlated and compared to Core Laboratory-adjudicated 30-day echocardiographic data.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2021 Tipo del documento: Article País de afiliación: Suecia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2021 Tipo del documento: Article País de afiliación: Suecia