Catching mono- and poly-ADP-ribose readers with synthetic ADP-ribose baits.

Cohen, Michael S

Cohen, Michael S.

Afiliación

Cohen MS; Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, OR 97239, USA. Electronic address: cohenmic@ohsu.edu.

Mol Cell ; 81(21): 4351-4353, 2021 11 04.

Article en En | MEDLINE | ID: mdl-34739826

RESUMEN

ADP-ribosylation is an essential post-translational modification that comes in two varieties: mono-ADP-ribosylation (MAR) and poly-ADP-ribosylation (PAR). Modular interaction domains that read MAR and PAR modifications are critical for interpreting the language of ADP-ribosylation. Kliza et al. (2021) use a chemical biology approach to identify distinct MAR and PAR readers.

Asunto(s)

Adenosina Difosfato Ribosa; Poli Adenosina Difosfato Ribosa; ADP-Ribosilación; Adenosina Difosfato Ribosa/metabolismo; Poli Adenosina Difosfato Ribosa/metabolismo; Procesamiento Proteico-Postraduccional

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Poli Adenosina Difosfato Ribosa / Adenosina Difosfato Ribosa Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article

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