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Immunisation with UB-312 in the Thy1SNCA mouse prevents motor performance deficits and oligomeric α-synuclein accumulation in the brain and gut.
Nimmo, Jacqui T; Smith, Harry; Wang, Chang Yi; Teeling, Jessica L; Nicoll, James A R; Verma, Ajay; Dodart, Jean-Cosme; Liu, Zhi; Lin, Feng; Carare, Roxana O.
Afiliación
  • Nimmo JT; Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Smith H; Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Wang CY; United Biomedical, Inc, Hauppauge, NY, USA.
  • Teeling JL; Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Nicoll JAR; Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Verma A; United Neuroscience, Dublin, Ireland.
  • Dodart JC; Vaxxinity, Dallas, TX, USA.
  • Liu Z; United Biomedical, Inc, Hauppauge, NY, USA.
  • Lin F; United Biomedical, Inc, Hauppauge, NY, USA.
  • Carare RO; Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK. R.O.Carare@soton.ac.uk.
Acta Neuropathol ; 143(1): 55-73, 2022 01.
Article en En | MEDLINE | ID: mdl-34741635
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastornos Parkinsonianos / Vacunas de Subunidad / Alfa-Sinucleína / Agregación Patológica de Proteínas Límite: Animals / Humans Idioma: En Revista: Acta Neuropathol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastornos Parkinsonianos / Vacunas de Subunidad / Alfa-Sinucleína / Agregación Patológica de Proteínas Límite: Animals / Humans Idioma: En Revista: Acta Neuropathol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido