Simulation of the oxidative metabolization pattern of netupitant, an NK<sub>1</sub> receptor antagonist, by electrochemistry coupled to mass spectrometry.

Chira, Ruxandra; Fangmeyer, Jens; Neaga, Ioan O; Zaharia, Valentin; Karst, Uwe; Bodoki, Ede; Oprean, Radu

Simulation of the oxidative metabolization pattern of netupitant, an NK₁ receptor antagonist, by electrochemistry coupled to mass spectrometry.

Chira, Ruxandra; Fangmeyer, Jens; Neaga, Ioan O; Zaharia, Valentin; Karst, Uwe; Bodoki, Ede; Oprean, Radu.

Afiliación

Chira R; Analytical Chemistry Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400349, Cluj-Napoca, Romania.
Fangmeyer J; University of Münster, Institute of Inorganic and Analytical Chemistry, 48149, Münster, Germany.
Neaga IO; Analytical Chemistry Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400349, Cluj-Napoca, Romania.
Zaharia V; Organic Chemistry Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012, Cluj-Napoca, Romania.
Karst U; University of Münster, Institute of Inorganic and Analytical Chemistry, 48149, Münster, Germany.
Bodoki E; Analytical Chemistry Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400349, Cluj-Napoca, Romania.
Oprean R; Analytical Chemistry Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400349, Cluj-Napoca, Romania.

J Pharm Anal ; 11(5): 661-666, 2021 Oct.

Article en En | MEDLINE | ID: mdl-34765280

Palabras clave

EC/LC/MS; Netupitant; Neurokinin-1 antagonist; Oxidative metabolism

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: J Pharm Anal Año: 2021 Tipo del documento: Article País de afiliación: Rumanía

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