Chemical Approaches for Studying the Biology and Pharmacology of Membrane Transporters: The Histidine/Large Amino Acid Transporter SLC7A5 as a Benchmark.

Scalise, Mariafrancesca; Scanga, Raffaella; Console, Lara; Galluccio, Michele; Pochini, Lorena; Indiveri, Cesare

Scalise, Mariafrancesca; Scanga, Raffaella; Console, Lara; Galluccio, Michele; Pochini, Lorena; Indiveri, Cesare.

Afiliación

Scalise M; Unit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata di Rende, Italy.
Scanga R; Unit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata di Rende, Italy.
Console L; Unit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata di Rende, Italy.
Galluccio M; Unit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata di Rende, Italy.
Pochini L; Unit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata di Rende, Italy.
Indiveri C; Unit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata di Rende, Italy.

Molecules ; 26(21)2021 Oct 29.

Article en En | MEDLINE | ID: mdl-34770970

Asunto(s)

Histidina/antagonistas & inhibidores; Transportador de Aminoácidos Neutros Grandes 1/metabolismo; Preparaciones Farmacéuticas/química; Biomarcadores/análisis; Biomarcadores/metabolismo; Biología Computacional; Histidina/metabolismo; Humanos; Transportador de Aminoácidos Neutros Grandes 1/genética

Palabras clave

SLC (SoLute Carriers); amino acids; blood brain barrier; cancer; membrane transport; placenta; protein ligands

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Preparaciones Farmacéuticas / Transportador de Aminoácidos Neutros Grandes 1 / Histidina Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Italia

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