Work productivity and activity impairment in patients with primary Sjögren's syndrome.
Clin Exp Rheumatol
; 39 Suppl 133(6): 93-99, 2021.
Article
en En
| MEDLINE
| ID: mdl-34796845
ABSTRACT
OBJECTIVES:
In this observational, analytical, cross-sectional study we aimed to describe the impact of primary Sjögren's syndrome (pSS) on work productivity and activities of daily living (ADL) to assess the association between ADL impairment and clinical manifestations and to compare ADL impairment according to patients' socioeconomic condition.METHODS:
Patients diagnosed with pSS attending 11 centres from Argentina were included. To evaluate work productivity and ADL impairment, a work productivity and activity impairment questionnaire (WPAI) was used. A multiple linear regression model was performed, considering deterioration on ADL due to health as a dependent variable, adjusted for potential confounders.RESULTS:
252 patients were included, 98.4% were women, with a mean age of 52.6 years (±14.8). The average percentage of time lost due to health was 15.7 hours (±30.1 95% CI 9.6-21.9); the decrease in work productivity was 27.2 (±30.2 95% CI 21.3-33.1), the total disability was 33.7 (±35.8 95% CI 26.4-4) and ADL deterioration was 34.2 (±30.9. 95% CI 30.4-38). In the multivariate analysis, xerostomia, arthritis and depression showed significant and independent association. The mean of ADL impairment was 38.2 (±30.7) in patients attending public centres versus 28 (± 30.6) in private centres, which was a statistically significant difference.CONCLUSIONS:
We found a compromise in all WPAI domains. Arthritis, xerostomia and depression were associated significantly and independently with ADL impairment. Deterioration in ADL was greater in patients treated in public centres. Considering these aspects will allow a better understanding of patients who suffer from this disease.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Actividades Cotidianas
/
Síndrome de Sjögren
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
/
Middle aged
País/Región como asunto:
America do sul
/
Argentina
Idioma:
En
Revista:
Clin Exp Rheumatol
Año:
2021
Tipo del documento:
Article
País de afiliación:
Argentina