Design, synthesis and biological evaluations of 2-aminothiazole scaffold containing amino acid moieties as anti-cancer agents.

Ilyas, Umair; Naz, Shagufta; Uz Zaman, Shahiq; Altaf, Reem; Nadeem, Humaira; Aun Muhammad, Syed; Faheem, Muhammad; Qadir, Muhammad Imran

Ilyas, Umair; Naz, Shagufta; Uz Zaman, Shahiq; Altaf, Reem; Nadeem, Humaira; Aun Muhammad, Syed; Faheem, Muhammad; Qadir, Muhammad Imran.

Afiliación

Ilyas U; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Naz S; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Uz Zaman S; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Altaf R; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Nadeem H; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Aun Muhammad S; Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan.
Faheem M; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Qadir MI; Institute of Molecular Biology & Biotechnology, Bahauddin Zakariya University, Multan, Pakistan.

Pak J Pharm Sci ; 34(4(Supplementary)): 1509-1517, 2021 Jul.

Article en En | MEDLINE | ID: mdl-34799326

Asunto(s)

Aminoácidos/química; Antineoplásicos/síntesis química; Antineoplásicos/farmacología; Diseño de Fármacos; Tiazoles/química; Animales; Antineoplásicos/farmacocinética; Artemia; Neoplasias Colorrectales/tratamiento farmacológico; Células HCT116; Humanos; Modelos Moleculares; Simulación del Acoplamiento Molecular; Estructura Molecular; Conformación Proteica

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Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tiazoles / Diseño de Fármacos / Aminoácidos / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Pak J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Pakistán

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