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Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling.
Lim, Shuhui; Boyer, Nicolas; Boo, Nicole; Huang, Chunhui; Venkatachalam, Gireedhar; Angela Juang, Yu-Chi; Garrigou, Michael; Kaan, Hung Yi Kristal; Duggal, Ruchia; Peh, Khong Ming; Sadruddin, Ahmad; Gopal, Pooja; Yuen, Tsz Ying; Ng, Simon; Kannan, Srinivasaraghavan; Brown, Christopher J; Verma, Chandra S; Orth, Peter; Peier, Andrea; Ge, Lan; Yu, Xiang; Bhatt, Bhavana; Chen, Feifei; Wang, Erjia; Li, Nianyu Jason; Gonzales, Raymond J; Stoeck, Alexander; Henry, Brian; Sawyer, Tomi K; Lane, David P; Johannes, Charles W; Biswas, Kaustav; Partridge, Anthony W.
Afiliación
  • Lim S; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
  • Boyer N; Merck & Co., Inc. Boston Massachusetts 02115 USA kaustav.biswas@merck.com.
  • Boo N; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
  • Huang C; Merck & Co., Inc. Boston Massachusetts 02115 USA kaustav.biswas@merck.com.
  • Venkatachalam G; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
  • Angela Juang YC; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
  • Garrigou M; Merck & Co., Inc. Boston Massachusetts 02115 USA kaustav.biswas@merck.com.
  • Kaan HYK; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
  • Duggal R; Merck & Co., Inc. Boston Massachusetts 02115 USA kaustav.biswas@merck.com.
  • Peh KM; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
  • Sadruddin A; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
  • Gopal P; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
  • Yuen TY; Agency for Science, Technology and Research (ASTAR) Singapore 138665 Singapore cwjohannes@gmail.com.
  • Ng S; Agency for Science, Technology and Research (ASTAR) Singapore 138665 Singapore cwjohannes@gmail.com.
  • Kannan S; Agency for Science, Technology and Research (ASTAR) Singapore 138665 Singapore cwjohannes@gmail.com.
  • Brown CJ; Agency for Science, Technology and Research (ASTAR) Singapore 138665 Singapore cwjohannes@gmail.com.
  • Verma CS; Agency for Science, Technology and Research (ASTAR) Singapore 138665 Singapore cwjohannes@gmail.com.
  • Orth P; Merck & Co., Inc. Kenilworth New Jersey 07033 USA.
  • Peier A; Merck & Co., Inc. Kenilworth New Jersey 07033 USA.
  • Ge L; Merck & Co., Inc. Kenilworth New Jersey 07033 USA.
  • Yu X; Merck & Co., Inc. West Point Pennsylvania 19486 USA.
  • Bhatt B; Merck & Co., Inc. West Point Pennsylvania 19486 USA.
  • Chen F; Merck & Co., Inc. West Point Pennsylvania 19486 USA.
  • Wang E; Merck & Co., Inc. West Point Pennsylvania 19486 USA.
  • Li NJ; Merck & Co., Inc. West Point Pennsylvania 19486 USA.
  • Gonzales RJ; Merck & Co., Inc. West Point Pennsylvania 19486 USA.
  • Stoeck A; Merck & Co., Inc. Boston Massachusetts 02115 USA kaustav.biswas@merck.com.
  • Henry B; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
  • Sawyer TK; Merck & Co., Inc. Boston Massachusetts 02115 USA kaustav.biswas@merck.com.
  • Lane DP; Agency for Science, Technology and Research (ASTAR) Singapore 138665 Singapore cwjohannes@gmail.com.
  • Johannes CW; Agency for Science, Technology and Research (ASTAR) Singapore 138665 Singapore cwjohannes@gmail.com.
  • Biswas K; Merck & Co., Inc. Boston Massachusetts 02115 USA kaustav.biswas@merck.com.
  • Partridge AW; MSD International Singapore 138665 Singapore awpartridge@gmail.com.
Chem Sci ; 12(48): 15975-15987, 2021 Dec 15.
Article en En | MEDLINE | ID: mdl-35024121
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Chem Sci Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Chem Sci Año: 2021 Tipo del documento: Article