Treatment of vitiligo with 308-nm light emitting diode: Our experience from a two-year follow-up of Chinese patients.
Photodermatol Photoimmunol Photomed
; 38(5): 489-494, 2022 Sep.
Article
en En
| MEDLINE
| ID: mdl-35075714
ABSTRACT
BACKGROUND:
A light emitting diode (LED), with a wavelength of 308 nm, has been utilized in the dermatologic treatment of vitiligo.OBJECTIVES:
We investigated the efficacy and safety of 308-nm LED for use in the treatment of vitiligo.METHODS:
We conducted a retrospective study of 70 stable-stage vitiligo patients (with a total of 99 lesions) who received 308-nm LED treatment at the Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College from June 2018 to June 2020. Treatment efficacy was evaluated after 8 treatment sessions, 16 treatment sessions, and the final treatment session, to estimate the percentage of re-pigmentation in the treated area. The Kruskal-Wallis test was used for data analysis.RESULTS:
Based on the final treatment session analysis of all 99 lesions, 0 lesions showed no response, 21 lesions showed poor response, 29 lesions showed moderate response, 23 lesions showed good response, and 26 lesions showed excellent response. The efficacy rate was 49.49%, and there was a significant correlation between the six distinct anatomical regions treated and re-pigmentation grade (χ2 = 13.419, p = .009). Among these regions, facial lesions showed the best response to treatment, while the hands and feet lesions showed the poorest response.CONCLUSIONS:
The clinical efficacy of 308-nm LED treatment is limited based on the treatment area. It demonstrated significant practical application in the treatment of vitiligo.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trastornos de la Pigmentación
/
Terapia Ultravioleta
/
Vitíligo
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Photodermatol Photoimmunol Photomed
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
DERMATOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
China