Contemporary Trends in the Nationwide Incidence of Primary Intracerebral Hemorrhage.
Stroke
; 53(3): e70-e74, 2022 03.
Article
en En
| MEDLINE
| ID: mdl-35109682
ABSTRACT
BACKGROUND:
We report contemporary trends in nationwide incidence of intracerebral hemorrhage (ICH) across demographic and regional strata over a 15-year period.METHODS:
Utilizing the Nationwide Inpatient Sample (2004-2018) and US Census Bureau data, we calculated ICH incidence rates for age, race/ethnicity, sex, and hospital region sub-cohorts across 5 consecutive 3-year periods (2004-2006 to 2016-2018). We fit Poisson and log binomial regression models to evaluate demographic and regional differences in ICH incidence and trends in prevalence of hypertension and past/current anticoagulant use among hospitalized ICH patients.RESULTS:
Overall, the annual incidence rate (95% CI) of ICH per 100 000 was 23.15 (23.10-23.20). The 3-year incidence of ICH (per 100 000) increased from 62.79 in 2004 to 2006 to 78.86 in 2016 to 2018 (adjusted incidence rate ratio, CI 1.11 [1.02-1.20]), coinciding with increased 3-year prevalence of hypertension and anticoagulant use among hospitalized ICH patients (adjusted risk ratio, CI hypertension-1.16 [1.15-1.17]; anticoagulant use-2.30 [2.14-2.47]). We found a significant age-time interaction, whereby ICH incidence increased significantly faster among those aged 18 to 44 years (adjusted incidence rate ratio, CI 1.10 [1.05-1.14]) and 45 to 64 years (adjusted incidence rate ratio, CI 1.08 [1.03-1.13]), relative to those aged ≥75 years.CONCLUSIONS:
Rising ICH incidence among young and middle-aged Americans warrants ICH prevention strategies targeting these economically productive age groups.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hemorragia Cerebral
/
Hipertensión
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
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Aged
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Aged80
/
Female
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Humans
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Male
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Middle aged
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Stroke
Año:
2022
Tipo del documento:
Article