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SARS-CoV-2-specific T cells are generated in less than half of allogeneic HSCT recipients failing to seroconvert after COVID-19 vaccination.
Jarisch, Andrea; Wiercinska, Eliza; Daqiq-Mirdad, Shabnam; Hellstern, Helen; Ajib, Salem; Cremer, Anjali; Nguyen, Ngoc Thien Thu; Dukat, Alexandra; Ullrich, Evelyn; Ciesek, Sandra; Chow, Kai-Uwe; Serve, Hubert; Seifried, Erhard; Bader, Peter; Bonig, Halvard; Bug, Gesine.
Afiliación
  • Jarisch A; Division of Pediatric Stem Cell Transplantation and Immunology, Goethe University, Frankfurt, Germany.
  • Wiercinska E; German Red Cross Blood Service BaWüHe, Frankfurt, Germany.
  • Daqiq-Mirdad S; German Red Cross Blood Service BaWüHe, Frankfurt, Germany.
  • Hellstern H; German Red Cross Blood Service BaWüHe, Frankfurt, Germany.
  • Ajib S; Department of Medicine, Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Cremer A; Department of Medicine, Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Nguyen NTT; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.
  • Dukat A; German Cancer Consortium (DKTK) Frankfurt/Mainz and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Ullrich E; Department of Medicine, Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Ciesek S; Outpatient Cancer Clinic AKS Schaubstraße, Frankfurt, Germany.
  • Chow KU; Division of Pediatric Stem Cell Transplantation and Immunology, Goethe University, Frankfurt, Germany.
  • Serve H; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.
  • Seifried E; German Cancer Consortium (DKTK) Frankfurt/Mainz and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Bader P; Experimental Immunology, Department for Children and Adolescent Medicine, Goethe University, Frankfurt, Germany.
  • Bonig H; Institute for Medical Virology, Goethe University, Frankfurt, Germany.
  • Bug G; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.
Eur J Immunol ; 52(7): 1194-1197, 2022 07.
Article en En | MEDLINE | ID: mdl-35389515
Little is known about the cellular immune response to SARS-CoV-2 vaccination in patients after HSCT and B-NHL with iatrogenic B-cell aplasia. In nonseroconverted HSCT patients, induction of specific T-cell responses was assessed. The majority of allogeneic HSCT patients not showing humoral responses to vaccination also fail to mount antigen-specific T-cell responses.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trasplante de Células Madre Hematopoyéticas / COVID-19 Límite: Humans Idioma: En Revista: Eur J Immunol Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trasplante de Células Madre Hematopoyéticas / COVID-19 Límite: Humans Idioma: En Revista: Eur J Immunol Año: 2022 Tipo del documento: Article País de afiliación: Alemania