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Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.
Falcinelli, Shane D; Peterson, Jackson J; Turner, Anne-Marie W; Irlbeck, David; Read, Jenna; Raines, Samuel Lm; James, Katherine S; Sutton, Cameron; Sanchez, Anthony; Emery, Ann; Sampey, Gavin; Ferris, Robert; Allard, Brigitte; Ghofrani, Simon; Kirchherr, Jennifer L; Baker, Caroline; Kuruc, JoAnn D; Gay, Cynthia L; James, Lindsey I; Wu, Guoxin; Zuck, Paul; Rioja, Inmaculada; Furze, Rebecca C; Prinjha, Rab K; Howell, Bonnie J; Swanstrom, Ronald; Browne, Edward P; Strahl, Brian D; Dunham, Richard M; Archin, Nancie M; Margolis, David M.
Afiliación
  • Falcinelli SD; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Peterson JJ; Department of Microbiology and Immunology, UNC School of Medicine, Chapel Hill, North Carolina, USA.
  • Turner AW; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Irlbeck D; Department of Microbiology and Immunology, UNC School of Medicine, Chapel Hill, North Carolina, USA.
  • Read J; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Raines SL; Division of Infectious Diseases, Department of Medicine, UNC, Chapel Hill, North Carolina, USA.
  • James KS; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Sutton C; HIV Drug Discovery, ViiV Healthcare, Research Triangle Park, North Carolina, USA.
  • Sanchez A; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Emery A; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Sampey G; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Ferris R; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Allard B; Department of Biochemistry and Biophysics, UNC School of Medicine, Chapel Hill, North Carolina, USA.
  • Ghofrani S; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Kirchherr JL; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Baker C; Department of Biochemistry and Biophysics, UNC School of Medicine, Chapel Hill, North Carolina, USA.
  • Kuruc JD; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Gay CL; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • James LI; HIV Drug Discovery, ViiV Healthcare, Research Triangle Park, North Carolina, USA.
  • Wu G; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Zuck P; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Rioja I; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Furze RC; Division of Infectious Diseases, Department of Medicine, UNC, Chapel Hill, North Carolina, USA.
  • Prinjha RK; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Howell BJ; Division of Infectious Diseases, Department of Medicine, UNC, Chapel Hill, North Carolina, USA.
  • Swanstrom R; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Browne EP; Division of Infectious Diseases, Department of Medicine, UNC, Chapel Hill, North Carolina, USA.
  • Strahl BD; UNC HIV Cure Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
  • Dunham RM; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, Chapel Hill, North Carolina, USA.
  • Archin NM; Department of Infectious Disease, Merck & Co. Inc., Kenilworth, New Jersey, USA.
  • Margolis DM; Department of Infectious Disease, Merck & Co. Inc., Kenilworth, New Jersey, USA.
J Clin Invest ; 132(8)2022 04 15.
Article en En | MEDLINE | ID: mdl-35426377
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Clin Invest Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Clin Invest Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos